Evaluation of Vaccination with Brucella abortus RB51 Strain in Herds Naturally Infected with Brucellosis in Productive Systems Found in Tropical Climate

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Brucella abortus RB51 induces protection in mice orally infected with the virulent strain B. abortus 2308.

Brucellae are gram-negative, facultative intracellular bacteria which are one of the most common causes of abortion in animals. In addition, they are the source of a severe zoonosis. In this trial, we evaluated the effect of oral inoculation of Brucella abortus RB51 in mice against a challenge infection with B. abortus 2308. First, we showed that a gastric acid neutralization prior to the oral ...

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Experiences in Mexico of the vaccination in bovines and goats, with Brucella abortus RB51 strain

The control of brucellosis in Mexico since the 70's until 1998 was performed using cattle vaccination with S19 strain of Brucella abortus as a key tool. The use of strain RB51 was approved since 1998 and vaccination with strain S19 was gradually decreased until fully waived. The strain S19 was used again from 2005 and now both vaccines are applied equally to prevent brucellosis in Mexican cattl...

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Safety of Brucella abortus strain RB51 in black bears.

In two studies conducted from October 1999 to March 2000 and December 2000 to April 2001, adult black bears (Ursus americanus) were orally inoculated with 1.4-3.1 x 10(10) colony-forming units (CFU) of Brucella abortus strain RB51 (SRB51, n=12) or 2 ml of 0.15 M NaCl solution (saline, n=11). We did not detect a difference (P>0.05) in antibody titers to SRB51 in serum obtained before vaccination...

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Immune responses of bison and efficacy after booster vaccination with Brucella abortus strain RB51.

Thirty-one bison heifers were randomly assigned to receive saline or a single vaccination with 10(10) CFU of Brucella abortus strain RB51. Some vaccinated bison were randomly selected for booster vaccination with RB51 at 11 months after the initial vaccination. Mean antibody responses to RB51 were greater (P < 0.05) in vaccinated bison after initial and booster vaccination than in nonvaccinated...

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ژورنال

عنوان ژورنال: International Journal of Dairy Science

سال: 2009

ISSN: 1811-9743

DOI: 10.3923/ijds.2009.109.116